Terrie Taylor's Research

Some recent papers — with many collaborators

Perspectives on Social and Behavior Problems in Cerebral Malaria Survivors in Blantyre, Malawi

Overdiagnosis of Malaria Illness in an Endemic Setting: A Facility-Based Surveillance Study in Malawi

School-based screening and treatment may reduce P. falciparum transmission

Revisiting Co-Trimoxazole Prophylaxis for African Adults in The Era of Antiretroviral Therapy: A Randomized Controlled Clinical Trial

Adipose tissue parasite sequestration drives leptin production in mice and correlates with human cerebral malaria

Population Attributable Fraction of Anemia Associated with P. falciparum Infection in Children in Southern Malawi

How Does Blood-Retinal Barrier Breakdown Relate to Death and Disability in Pediatric Cerebral Malaria?

Central Nervous System Virus Infection in African Children with Cerebral Malaria

Diffusion-Weighted MR Imaging in a Prospective Cohort of Children with Cerebral Malaria Offers Insights into Pathophysiology and Prognosis

Comparison of CD8+ T Cell Accumulation in the Brain During Human and Murine Cerebral Malaria

Binding Heterogeneity of Plasmodium falciparum to Engineered 3D Brain Microvessels Is Mediated by EPCR and ICAM-1. 2019 Meta-analysis of Plasmodium falciparum

Submicroscopic malaria infection is not associated with fever in cross-sectional studies in Malawi

Cerebral malaria is associated with differential cytoadherence to brain endothelial cells

Parasite histones are toxic to brain endothelium and link blood barrier breakdown and thrombosis in cerebral malaria

Central Nervous System Virus Infection in African Children with Cerebral Malaria

Automated Detection of Malarial Retinopathy in Retinal Fundus Images obtained in Clinical Settings

CD8+ T cells target cerebrovasculature in children with cerebral malaria

Data for: Dose Finding Study of Pentoxifylline in Children With Cerebral Malaria

CD8+ T cells target cerebrovasculature in children with cerebral malaria

Neurovascular sequestration in paediatric P. falciparummalaria is visible clinically in the retina

Parasite histones mediate leak and coagulopathy in cerebral malaria

Barriers and Facilitators to Obtaining Informed Consent in a Critical Care Pediatric Research Ward in Southern Malawi

Neurodevelopmental Impairments 1 Year After Cerebral Malaria

Researchers at LSTM show that parasites from patients with cerebral malaria stick preferentially in their brains

Brain swelling is independent of peripheral plasma cytokine levels in Malawian children with cerebral malaria

Type I Interferon Receptor Variants in Gene Regulatory Regions are Associated with Susceptibility to Cerebral Malaria in Malawi.

Simulation models predict that school-age children are responsible for most human-to-mosquito Plasmodium falciparum transmission in southern Malawi.

Noninvasive measures of brain edema predict outcome in pediatric cerebral malaria.

Cerebrospinal fluid Plasmodium falciparum histidine-rich protein-2 in pediatric cerebral malaria.

A targeted approach for routine viral load monitoring in Malawian adults on antiretroviral therapy.

Pathology-Based Research in Africa.

1.5 Tesla Magnetic Resonance Imaging to Investigate Potential Etiologies of Brain Swelling in Pediatric Cerebral Malaria.

NIH Awards MSU Research $8.4 Million to Develop First Malaria Treatments

While the world waits for a vaccine against the ancient disease malaria, Terrie E. Taylor is working to save the lives of children who are currently afflicted by the deadliest form of the disease. Taylor, MSU University Distinguished Professor of internal medicine and an osteopathic physician, will use an $8.4 million grant from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health to build on her groundbreaking researchthat was published in the New England Journal of Medicine in 2015. Taylor and her team discovered children with cerebral malaria develop massively swollen brains that are forced out through the bottom of the skull and compress the brain stem. The pressure causes the children to stop breathing and die. Read more in MSU Today.

Terrie Taylor's Presentation at World Malaria Day

Terrie Taylor's talk, The Pathogenesis of Fatal Cerebral Malaria: A Few More Pieces of the Puzzle, described her work to characterize and treat this deadly complication among young children in Malawi. In this area of Africa, the burden of disease of malaria falls largely on children between the ages of one and three. Children who develop cerebral malaria experience seizures and often become comatose. Death is usually related to respiratory arrest, although the exact process that leads to death in these children has until recently been somewhat of a mystery. See the full presentation.

New malaria tool shows which kids at greatest risk

Researchers at Michigan State University have identified a test that can determine which children with uncomplicated malaria are more likely to develop cerebral malaria, a life-threatening form of the disease. Read more.

Uncovering how cerebral malaria damages the brain

Building on more than a quarter century of work in Malawi, work which includes the first systematic magnetic resonance imaging (MRI) studies, Dr. Karl Seydel, a Michigan State University researcher and colleague of Dr. Taylor’s, is traveling to neighboring Zambia to help characterize patients who will undergo MRI scans on a stronger MRI machine. The comparisons between images from patients in Malawi and images from similar patients in Zambia will illuminate our understanding of how malaria damages the pediatric brain. Read more.

Taylor receives national honor for work with malaria in Malawi

For her years of dedicated work in Africa studying and treating malaria, Michigan State University's Terrie Taylor is being honored with a 2011 American Medical Association Foundation Excellence in Medicine Award. Read more.

Terrie Taylor's research
has been featured in
numerous publications.

To view a full list, click here.